4 things to know about Bile Acid Synthesis Disorder (BASD)

4 things to know about Bile Acid Synthesis Disorder (BASD)

BASD or Bile Acid Synthesis Disorder is a rare metabolic disorder that results from defects in the production of bile acids in the body. Bile acids are essential chemical compounds secreted in the liver. These are required for the absorption of fat and fat-soluble vitamins in the intestines. Bile acid synthesis is a process that involves the breakdown and elimination of cholesterol in the body. Bile acid synthesis disorder results in the accumulation of excess bile acids, which lead to a lot of health complications, including organ failure. Read on to know more about BASD. What causes Bile Acid Synthesis Disorder (BASD)? Genetic mutations cause Bile Acid Synthesis Disorder (BASD). The mutations cause improper synthesis of cholic acid and chenodeoxycholic acid, which are two primary bile acids. These acids are synthesized by the liver. This process involves complex chemical reactions of 27 enzymatic steps inside hepatocytes, which are special liver cells. A specialized protein known as the enzyme is required at each step of the bile acid synthesis. This specific enzyme is produced by a gene associated with a specific bile acid disorder. BASD occurs when there is a mutation of a specific gene that is responsible for decoding a bile acid enzyme.
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Causes and symptoms of myelofibrosis

Causes and symptoms of myelofibrosis

Causes and symptoms of myelofibrosis Though the progress in medical science over the years has eradicated major diseases from the face of the earth, there are certain health conditions that are yet to be completely treated. One such ailment that is invincible till date and continues to claim lives is cancer. Cancer can affect any part of the body and is only treatable when it is diagnosed in its earlier stages. One such form of cancer that affects the bone marrow is called myelofibrosis. Myelofibrosis is that type of bone marrow cancer that affects the body’s ability to produce blood cells. In fact, myelofibrosis is a part of a group of conditions called myeloproliferative neoplasms (MPNs), which cause the bone marrow to stop developing and functioning the way it should. This causes fibrous scar tissue. This form of cancer can be primary (occurs on its own) or secondary (occurs due to some other condition that affects the bone marrow). Moreover, the other MPNs can progress and gradually turn into myelofibrosis over a period of time. Causes of myelofibrosis This condition is caused by a genetic mutation in the blood stem cells. It affects the blood stem cells’ ability to replicate and divide into the multiple specialized cells that make up the blood.
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Everything you need to know about preeclampsia

Everything you need to know about preeclampsia

Everything you need to know about preeclampsia A form of pregnancy complication, preeclampsia damages organ systems, typically the liver and kidneys. It is characterized by hypertension, which often begins to act up post 20 weeks of pregnancy. If this condition is left untreated, it can cause some life-threatening consequences for both the mother and the baby. Apart from hypertension, here are some signs and symptoms of preeclampsia: Severe headaches Proteinuria, that is, excessive protein content in the urine Nausea and vomiting Pain in the upper abdomen and under the right side of the ribs Insufficient number of platelets in the blood Vision problems such as sensitivity, blurred vision, or temporary blindness Liver malfunction Fluid buildup in the lungs that causes breathlessness Unusual weight gain and edema, that is, swelling that particularly affects the face and arms Causes of preeclampsia Preeclampsia is a result of multiple factors. Medical researchers believe that it starts in the placenta, an organ that is responsible for nourishing the fetus through the course of pregnancy. In the initial stages of pregnancy, new blood vessels form to ensure that sufficient blood is delivered to the placenta. However, some women develop blood vessels that fail to function efficiently.
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Ways to treat and prevent hives
Skin

Ways to treat and prevent hives

Skin is one of the largest external organs in the body. On a daily basis, our skin comes in direct contact with a lot of things that could either be sanitized or dirty. Fortunately, the immune system of our body constantly protects every organ, the skin in this context, from foreign substances that could prove to be harmful to our body. However, at times, due to several reasons, some people get exposed to certain allergens that cause the skin to get hives. Hives are medically known as urticaria, which is an outbreak of swollen red- or skin-colored bumps that appear like skin rashes and are itchy in nature. Appearance and characteristics When a person is suffering from hives, their body will appear to have several raised and itchy bumps with a skin- or red-colored surface. Upon applying pressure on the hives, they can appear to be blanching, and the red hives turn white when pressed. An important thing to know about hives is that it can appear on any part of the skin and can change its shape. Hives also appear and disappear or reappear over short periods of time. Hives are either acute (short-lived) or chronic (long-term); in either case, they don’t cause any harm to the body unless they appear in the throat and the swelling causes restrictions in breathing.
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5 effective home remedies for GERD
Wellness

5 effective home remedies for GERD

It is normal to experience unpleasant sensations when something that you ate doesn’t agree with you. However, when any kind of food, whether spicy or bland, evokes a string of unpleasant sensations, there’s something seriously wrong with the digestive system. One such condition that is known to cause a hot and burning sensation in the throat which is followed by unusual pressure in the chest is called gastroesophageal reflux disease (GERD). One of the major symptoms of GERD is heartburn and acid reflux. In fact, if one experiences mild acid reflux twice a week or moderate to severe acid reflux at least once a week, then they are diagnosed with GERD. GERD can often be resolved with the help of over-the-counter (OTC) medications or by making major lifestyle changes. In certain severe cases where GERD cannot be controlled by medications, surgery is the only viable option. However, there are some effective ways of managing the symptoms of GERD and this proves beneficial in the long run. Some of the home remedies that can be used to manage the symptoms of GERD are: Use baking soda – Acid reflux is the major symptom of GERD, and if you wish to seek instant relief from the same, try using baking soda.
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An overview of growth hormone deficiency
Hormones

An overview of growth hormone deficiency

Our body has many essential components that help the body function normally. One of the many components is the hormones, which are the chemical messengers of the body. They travel to the tissues and organs in the body through the bloodstream. Although they are essential for the body, they work slow and affect different parts of the body over time. Hormones are responsible for several functions like growth and development, metabolism, reproduction, moods, and sexual function. All hormones come from the endocrine glands. There are different types of endocrine glands, that is, pituitary, thymus, thyroid, adrenal glands, pancreas, and pineal gland. A small hormonal change can cause drastic changes in the body. This shows how powerful hormones really are. One of the hormones important for the growth of the human body is called somatotropin or the human growth hormone. It is produced in the pituitary gland and plays an important role in the composition, metabolism, cell repair, and growth of the body. Additionally, the growth hormone also boosts muscle growth and promotes strength and exercise performance. It also helps the body recover from injuries and diseases. On rare occasions, people suffer from a defect where they face a deficiency of growth hormone, called the growth hormone deficiency.
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7 foods to help with hypertension
Food

7 foods to help with hypertension

Hypertension is caused due to high blood pressure that occurs when there is increased pressure of blood against the artery walls. If not detected on time, the increased pressure can cause damage to blood vessels. This can lead to stroke, heart diseases, and kidney disease. Hypertension does not have any early signs and symptoms. It a long-term chronic health problem that does not have a permanent cure, but it can be easily managed with medication, exercise, and diet. To control hypertension, one of the simplest ways is to manage one’s diet. Excess sodium in the body is one of the major triggers of high blood pressure. By adding certain food groups to the diet, one can control the intake of sodium. Read on to know more about the various foods that help in hypertension management. Dark chocolate : Eating about 100 grams of dark chocolate in a day may lower the risk of cardiovascular diseases and hypertension. Chocolate that has more than 60 percent cocoa solids and a lower percentage of sugar is considered good for health. Dark chocolate can be added to fruits or yogurt as a nutritious alternative for dessert. Green leafy vegetables : Leafy vegetables are rich sources of potassium.
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Know about the seven common symptoms of asthma
Asthma & Allergy

Know about the seven common symptoms of asthma

Asthma is a disease of the airways to the lungs. It is an inflammatory disease that makes it difficult to breathe and in some cases, even impossible. It is one of the most common chronic conditions among children. When the lining of the airways swell and the muscles around them tighten, it causes asthma. Further, the mucus fills through the airways that reduce the amount of air passing through them. Symptoms of asthma The symptoms that one may experience during asthma tends to vary based on the type of asthma. The symptoms of asthma are quite prevalent and hence, diagnosed easily. Even if one is having their first onset of asthma or has been diagnosed for many years, there are certain symptoms commonly experienced by them. Some of these common symptoms of asthma include: Coughing One of the most common symptoms of asthma is a persistent cough. A cough may be wet if it contains mucus or even dry. It usually gets worse in the night or during exercise. If one does not experience any other symptom of asthma other than coughing, it might be a symptom of cough-variant asthma. Fatigue When one is diagnosed with asthma, they usually don’t get enough of oxygen into their lungs.
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6 major causes of goiter
Hormones

6 major causes of goiter

6 major causes of goiter There are several glands in the body, each of which secretes hormones that aid essential bodily functions. Like every other part of the body, even these glands are prone to disorders. One such disorder that arises due to a malfunctioning thyroid gland is called goiter. This condition is characterized by an abnormal enlargement of the thyroid gland. In goiter, the thyroid, which is a butterfly-shaped gland located at the base of the neck, swells abnormally and becomes visible. Goiter is often attributed to the lack of iodine in one’s diet, but there are other underlying health conditions that cause goiter as well. Though goiter is not a life-threatening disease, goiter can make it difficult for the individual to swallow or breathe. Usually, the size of the goiter is what determines whether one needs immediate treatment for the same or they can go about their life as usual. Read on to know more about goiter, as it will come in handy in identifying the disease and seeking timely help for the same. Causes of goiter Though goiter has been attributed to the lack of iodine in our diet, this condition is also caused by other underlying health conditions.
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5 easy ways to lower high triglycerides level
Heart

5 easy ways to lower high triglycerides level

There are several factors that affect an individual’s health, right from the diet they consume to the type of lifestyle they lead. Everything plays a major role in determining the quality of life of an individual. Usually, people pay a lot of attention to their blood pressure and cholesterol levels because if these go haywire, their health will soon experience a downward spiral. Apart from these two factors, another important factor that you should monitor are the triglycerides. Triglycerides are a type of fat, also known as lipid, that is found in the blood. When one eats, the body converts the calories that aren’t needed immediately into triglycerides, which are stored in the fat cells. These triglycerides are released by the hormones for energy between meals. The trouble brews when one consumes more calories than they burn, and this results in higher levels of triglycerides. High levels of triglycerides result in the thickening of the arteries and increase the risk of heart disease or stroke. So, to lower the levels of triglycerides in the body, one can adhere to the following steps: Lose weight The major cause of increasing levels of triglycerides is consuming more calories than you burn. Which is why losing weight is an effective way of lowering the levels of triglycerides in the blood.
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